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Skin Conditions: atrophic=thin, wrinkled, blister=fluid-filled bump, crust/scab=formation of dried blood, pus, or other skin fluid over a break in the skin, cyst=deep lesion that is filled with pus, excoriation=hollowed-out or linear area covered by a crust, hives/wheals=pink swelling of the skin, lichenification=skin that has thickened, macule=smaller version of a patch; a flat discolored spot, nodule/papule=solid, raised bump, raised bumps=bumps that stick out above the skin surface, patch=flat, discolored spot, pustule (pimple)=inflamed lesions that look like pink bumps, scales=dead skin cells that look like flakes or dry skin, scar=fibrous tissue that has formed after a skin injury Benzoyl peroxide cream is a Topical bactericidals. Widely available OTC bactericidal products containing benzoyl peroxide may be used in mild to moderate acne. The gel or cream containing benzoyl peroxide is rubbed, twice daily, into the pores over the affected region. Bar soaps or washes may also be used and vary from 2 to 10% in strength. In addition to its therapeutic effect as a keratolytic (a chemical that dissolves the keratin plugging the pores) benzoyl peroxide also prevents new lesions by killing P.acnes. In one study, roughly 70% of participants using a 10% benzoyl peroxide solution experienced a reduction in acne lesions after 6 weeks.Unlike antibiotics, benzoyl peroxide has the advantage of being a strong oxidizer (essentially a mild bleach) and thus does not appear to generate bacterial resistance. However, it routinely causes dryness, local irritation and redness. A sensible regimen may include the daily use of low-concentration (2.5%) benzoyl peroxide preparations, combined with suitable non-comedogenic moisturisers to help avoid overdrying the skin. Care must be taken when using benzoyl peroxide, as it can very easily bleach any fabric or hair it comes in contact with. Blue and red light Acne Treatment It has long been known that short term improvement can be achieved with sunlight. However, studies have shown that sunlight worsens acne long-term[citation needed]. More recently, visible light has been successfully employed to treat acne (phototherapy) - in particular intense violet light (405-420nm) generated by purpose-built fluorescent lighting, dichroic bulbs, LEDs or lasers. Used twice weekly, this has been shown to reduce the number of acne lesions by about 64%; and is even more effective when applied daily. The mechanism appears to be that a porphyrin (Coproporphyrin III) produced within P. acnes generates free radicals when irradiated by 420nm and shorter wavelengths of light. Particularly when applied over several days, these free radicals ultimately kill the bacteria. Since porphyrins are not otherwise present in skin, and no UV light is employed, it appears to be safe, and has been licensed by the U.S. FDA. The treatment apparently works even better if used with red visible light (660 nanometer) resulting in a 76% reduction of lesions after 3 months of daily treatment for 80% of the patients; and overall clearance was similar or better than benzoyl peroxide. Unlike most of the other treatments few if any negative side effects are typically experienced, and the development of bacterial resistance to the treatment seems very unlikely. After treatment, clearance can be longer lived than is typical with topical or oral antibiotic treatments; several months is not uncommon. The equipment or treatment, however, is relatively new and reasonably expensive to buy initially, although the total cost of ownership can be similar to many other treatment methods (such as the total cost of benzoyl peroxide, moisturiser, washes) over a couple of years of use. |
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